Part 7

## active cathartic, producing sharp effects in doses of 30-60 centigrams;

in fact it produces such severe tenesmus that its use in such doses should not be recommended.

The root bark is used internally in an infusion (4-8 grams to 1 liter of water) as an emollient in irritability of the bladder and urethra and has been recommended for such a purpose by Mooden Sheriff. It is a diuretic which frequently acts as a purgative, a fact that is not surprising in view of the above-mentioned properties of the alcoholic extract.

The roasted seeds used as a purgative are so trustworthy that they deserve the further attention of physicians.

Botanical Description.--A vine very well known by its blue flowers. Leaves alternate with 3 pairs of oval leaflets. Stipules persistent. Flowers axillary, solitary, 1-1 1/2' in long diameter. Calyx in 5 acute divisions, the two upper ones smaller. Corolla papilionaceous. Standard open, notched at the end. Keel shorter than the wings and covered by them. Stamens 10, 9 united and 1 free. Stigma downy, thick. Pod full of short hairs, with more than 6 surrounded with a tow-like substance, reniform, with black spots.

Habitat.--Common along the roads and in gardens. Flowers in July and November.

_1. Pterocarpus santalinus_, L. [5]

Nom. Vulg.--_Narra_, _Naga_, Tag.; _Apalit_, _Daytanag_, Pam.; _Red Saunders_ or _Red Sandalwood Tree_, Eng.

_2. P. Indicus,_ Willd. (_P. pallidus_, Blanco.)

Nom. Vulg.--_Asana_, Tag.; _Naga_, Vis.

_3. P. erinaceus_, Poir. (_P. echinatus_, Pers. & DC.)

Nom. Vulg.--_Asana_, _Narra_, Tag.

Uses.--The wood of the first is the so-called "red sandalwood." It is used for building purposes and, in medicine, as an astringent. In decoction it is used as a gargle for sore throat. The second is also an excellent building material and is used medicinally for its astringent properties. A decoction of sufficient strength to color the water a light blue is used as a mouth wash in toothache and has some reputation as a solvent of vesical calculi. All three species yield a resin known in pharmacy under the name of "kino." The true gum kino is really produced by the _P. marsupium_, Roxb., but the Philippine product, especially that of the second and third species, has for a long time been exported to Europe under the name of "red astringent gum" or "kino." This name is given to the sap of these trees dried without the aid of artificial heat. The bark is the part which produces it and the following extractive process is employed in Madras: a vertical incision is made in the trunk and lateral incisions perpendicular to it and a receptacle is placed at the foot of the tree. This soon fills and when the gum is sufficiently dried by air and sun it is packed in boxes and exported.

In respect to appearance, solubility and chemical composition, Flückiger and Hanbury were unable to discover any difference between the kino of _P. marsupium_, Roxb., and that of _P. erinaceus_, Poir. It is therefore interesting to consider a product that is identical with that described in the pharmacopoeias as produced by the _P. marsupium_, Roxb., though the latter does not grow in the Philippines.

Kino is at present used but little in therapeutics and its action is analogous to that of tannin and catechu. It is given internally for its astringent effect in chronic diarrhoea, leucorrhoea, blenorrhoea and hemorrhages. The dose of the powder is 1-4 grams, and of the alcoholic tincture, containing 20 parts kino to 100 of alcohol, 5-10 grams. In prolapse of the rectum and anal fissure the following solution is used by enema:

Kino 3 grams. Water 500 grams.

For vaginal injections a solution of 20 to 250 water.

Botanical Description.--The "pterocarpus," L., is a tree of the first order with odd-pinnate leaves. Leaflets alternate and coriaceous. Flowers yellow, in racemes, with caducous bracts and bractlets. Calyx turbinate, with short teeth. Petals exserted, markedly unguiculate. Standard and wings curled. Keel obtuse with its petals slightly or not at all coherent. The staminal tube, cleft above and below or above only. Stamens superior, often almost, and at times entirely, free. Anthers versatile. Ovary pedunculate, with 2 ovules. Style curved. Stigma terminal. Pod orbicular, smooth or spiny, usually containing one seed, encircled by a broad, rigid wing, the point curved downward.

Habitat.--In the mountains of Luzon, Panay and Mindoro. Blooms in March.

_Pongamia glabra_, Vent. (_Robinia mitis_, L.; _Gadelupa maculata_, Blanco.)

Nom. Vulg.--_Balikbalik_, Tag.; _Butong_, Vis.

Uses.--The oil expressed from the seeds is used in India for lighting purposes, and in addition is of notable therapeutic value. It is an excellent local remedy for the itch, for herpes and especially for pityriasis versicolor, used alone or emulsified with lemon juice. In stubborn cases Dymock recommends the addition of oil of _hydrocarpus_, camphor and powdered sulphur. Dr. Gibson states that he knows of no plant in the vegetable kingdom possessing more notable curative properties in itch, herpes and other cutaneous diseases than the plant under consideration. It is also used as an embrocation in articular rheumatism.

The powdered leaves mixed with common salt and pepper are given internally with a little milk, as a remedy for leprosy.

The juice of the root makes a useful wash for gangrenous ulcers and a good injection for fistula.

Botanical Description.--A tree, 18° high, with leaves opposite, odd-pinnate. Leaflets in 3 pairs, ovate, lanceolate, entire, glabrous and membranaceous. Flowers slightly spotted, racemose. Calyx bell-shaped, with 5 scarcely visible toothlets. Corolla papilionaceous, petals equal, clawed. Standard with 2 callosities athwart the base. Stamens 10, diadelphous. Pod with one seed, which is flat, smooth, veined, bright red.

Habitat.--Luzon and Panay. Blooms in October.

LEGUMINOSÆ.

Brasiletto Family.

_Cæsalpinia Bonducella_, Flem. (_Guilandina Bonducella_, L.)

Nom. Vulg.--_Bayag-Kambing_, _Kalambibit_, Tag.; _Dalugdug_, Vis.; _Fever Nut_, _Physic Nut_, _Bonduc Seeds_, Indo-Eng.

Uses.--The seed is the part of the plant employed and is official in the Pharmacopoeia of India. It is used as a tonic and antiperiodic in intermittent fevers and in general where tonic treatment is indicated. It has given good results in the malarial fevers of India, according to English physicians. The Pharmacopoeia of India contains the following preparation under the name of "Compound Powder of Bonduc" (Pulvis bonducellæ compositus).

Seeds of Bonduc, powdered 30 grams. Pepper 30 grams.

Mix and keep in a well-corked flask.

Dose.--1-2 grams 3 times a day.

In the Philippines the powdered seed is given in affections of the digestive tract, especially in diarrhoea and feeble digestion. The same name of Bonduc is given to the seeds of another species that grows in the Philippines, _C. Bonduc_, Roxb.; _Kamot-Kabag_, _Bayan-Kambing_, Tag. The seeds are identical in chemical composition and therapeutic indication.

The two principal substances contained in the seeds are an oil, 24% and a resin, 1.88%. The former is straw-colored and slightly bitter by virtue of the presence of a resin that may be precipitated by alcohol. The resin or bitter principle exists as an amorphous powder, white, bitter, not acrid, soluble in chloroform, alcohol, acetone, crystallizable acetic acid, fixed and essential oils; slightly soluble in ether and bisulphide of carbon, insoluble in water and petroleum ether. The alkalies do not affect it. It melts at 140°, decomposing and leaving only a carbon. Its discoverers, Heckel and Schlagdenhauffen, have given it the name _bonducin_ (C_14_H_15_O_5_). Hydrochloric acid colors it red; sulphuric acid, a maranthin red in half an hour.

Bonducin seems to be the active principle of the seeds and is given internally in doses of 10-20 centigrams; according to Dr. Isnard, of Marseilles, this dose has given as good results in fevers as the same quantity of quinine.

Botanical Description.--A shrub with prostrate stem bristling with thorns. Leaves twice abruptly pinnate, a thorn taking the place of the terminal leaflet. Leaflets in 10-14 pairs, ovate, expanded, with a spine at the apex. Common petioles thorny, with 4 leaf-like stipules at the base. Flowers yellow, in racemes. Calyx 5-parted, curved downward. Corolla inserted on the calyx, 5 petals, 4 nearly equal, the uppermost broader and shorter. Stamens 10. Filaments very unequal in height, inserted on the calyx, united and woolly at the base. Pistil very short. Stigma thick. Pod rhomboidal before maturity, prickly, containing 2 semi-globose seeds with testa hard, mottled and tough.

The other species, _C. Bonduc_, Roxb., is distinguished by leaflets unequal at the base, by the absence of stipules, and by the bright orange yellow seeds.

Habitat.--Common in Luzon, Panay and Joló. Blooms in December.

_Cæsalpinia Sappan_, L.

Nom. Vulg.--_Sibukao_, _Sapag_, Tag.; _Palo del Brasil_, Sp.; _Sappan Wood_, Eng.

Uses.--The decoction of Sibukao is given in hemorrhages, especially of the lungs. It is probably the red color of this decoction which originated the idea of giving it to check bleeding, and this is the practice of the native Filipino doctors, as well as of the Arabs and Hindoos. The natives of Cochin China, reasoning in an opposite manner, prescribe it as emmenagogue. Some authors recommend Sibukao as a substitute for logwood. The decoction is administered in chronic diarrhoea, especially that of children. A few cases of phlebitis have been reported as occasioned by its use. The extract is made as follows:

Sibukao in small pieces 500 grams. Boiling water 4 1/2 liters.

Macerate for 24 hours, boil until reduced by half, filter and evaporate the filtrate to a syrupy consistency. Do not use iron vessels.

Sibukao contains much tannin and gallic acid, and a peculiar substance which distinguishes it from logwood, _brasilin_ (C_22_H_20_O_7_), which gives a red color to alkaline solutions instead of blue or purple. It is a crystalline pigment which may be considered a compound of hematoxylon and fenol.

Botanical Description.--A very common tree, 12-15° high, with spiny trunk, leaves twice abruptly pinnate. Leaflets linear, notched at the apex. Flowers racemose. Calyx boat-shaped. Corolla, 5 petals, the uppermost broad, short, spotted red. Stigma bifid. Pod sabre-like, woody, with 3-4 seeds separated by partitions. The wood is well known everywhere in the Philippines, being a very important article of commerce, and there is no fear of logwood being substituted for it, as the latter is more expensive, and substitutions are not ordinarily made under such circumstances. In commerce it occurs in large pieces of all shapes and forms, since the branches and trunks are cut into pieces which vary from 1/2-2 meters in length. Its color is reddish-yellow or white with more or less red grain. Blooms in September.

_Cæsalpinia pulcherrima_, Swartz. (_Poinciana pulcherrima_, L. & Blanco.)

Nom. Vulg.--_Flores y Rosas Caballero_, _Caballero_, Sp.-Fil.; _Barbadoes Flower-Fence_, Eng.

Uses.--The leaves are emmenagogue, purgative like those of senna, and excitant. The bark especially is a powerful emmenagogue, used in some countries for criminal purposes. The decoction of the flowers is pectoral and febrifuge and is given in bronchitis, asthma and malarial fever. The flowers contain a bitter principle. The roots are acrid and poisonous. The seeds of the green fruit are eaten frequently by children; when ripe they contain gallic and tannic acids, by virtue of which they are used in tanning hides and to dye yellow combined with alum, and black combined with salts of iron. They also contain a pigment and a resin.

Infusion of the Flowers.--

Flowers of the caballero, dry 20 grams. Water 500 grams. Sugar 70 grams.

Mix. Dose, a wineglassful several times a day.

Botanical Description.--A shrub, with prickly trunk. Leaves twice abruptly pinnate. Leaflets 5-8 pairs, glabrous, ovate and elliptical, bearing a spine at the extremity, 3 stipules to each pair of leaflets. Flowers yellow and red, in racemes on the ends of the branches. Calyx divided almost to the base, with 5 concave parts. Corolla, 5 petals 1' long with short claws, one petal very small and straight, the others larger, with wavy edges. Stamens 10, crimson, 3' long, free, woolly, united at the lower end. Pistil the same length as the stamens. Stigma somewhat concave. Ovary sessile, unilocular, many-ovuled. Pod compressed, with 7 or more seeds inserted on the superior suture and separated from each other by fleshy divisions.

Habitat.--Very common in gardens where it is cultivated for its beautiful flowers. Blooms throughout the entire year.

_Cassia fistula_, L.

Nom. Vulg.--_Cañafistula_, Sp.; _Lombayong_, _Ibabaw_, _Baloyong_, Vis.; _Purging Cassia_, Eng.

Uses.--The pod known in pharmacy under the name of "Cañafistula" contains a blackish, sweet pulp, which is a mild purgative if combined with carminatives, but it produces severe colic if given alone. The urine sometimes takes on a dark color after taking it. The laxative dose is 4-8 grams, the purgative 30-60.

Extract of Cassia.--

Pulp and seeds of ripe pods 1 kilo. Water 1 liter.

After mixing the pulp with water the liquid is strained through a woolen cloth; the material which remains in the strainer is washed with a little more cold water which is added to the other liquid and the two are evaporated to the consistency of the extract.

Dose.--15-30 grams.

Dr. Irving states that the root is a very energetic purgative. In Concan the juice of the tender leaves is used in the treatment of impetigo.

Botanical Description.--A tree with trunk about as thick as the human body, with leaves opposite and abruptly pinnate. Leaflets, the lower ones smaller, 5 pairs, ovate, lanceolate, glabrous and rather tough. Common petiole, cleft at the base, lacking glandule. Flowers bright yellow, in long, pendulous racemes. Calyx, 5 ovate sepals. Corolla, 5 unequal petals. Stamens 10, free, 3 longer than the rest. Ovary unilocular, many-ovuled. Pod cylindrical, pointed at the end, woody, black, 1-2° long, with many circular seeds, surrounded by a blackish pulp and separated by partitions.

Habitat.--Common in Luzon and Panay. Blooms in March.

_Cassia occidentalis_, L.

Nom. Vulg.--_Tighiman_, _Balotangaso_, Tag.; _Tambalisa_, Vis.; _Western Senna_, _Styptic Weed_, Eng.; _Negro Coffee_, Indo-Eng.

Uses.--In Brazil they use an infusion of the root as a tonic and diuretic, 4 grams of the root bark and 180 of boiling water to be taken in one day. In Dahomey the leaves are used as a febrifuge. Thirty grams of fresh leaves are boiled in 300 grams of water till the liquid is reduced to 250 grams. The patient takes this decoction hot the first day of the fever and a profuse perspiration promptly breaks out. As a rule the effect is immediate and the fever does not recur. This treatment of fevers is more common in that country than that by quinine and they claim that it has the advantage over the latter of acting as a stomachic tonic. By adding a small quantity of the roots to the decoction it is rendered diuretic. The seeds possess the same properties and are used in decoctions of 30 grams to 300 of water. According to De Lanesan the roasted seeds are used in La Réunion in infusion similar to coffee in the treatment of gastralgia and asthma. In some countries they mix them with coffee just as chicory is used in Europe.

Heckel and Schlagdenhauffen have made a very complete study of the plant and we quote the following from their works:

Chemical composition of the seeds.--

Water 8.850 Fats and pigments soluble in petroleum ether 1.600 Fats and pigments soluble in chloroform 1.150 Odorous material and traces of tannin 5.022 Glucose 0.738 Gummy, mucilaginous and pectic matter 15.734 Soluble albuminoids and aleuron 6.536 Cellulose 7.434 Insoluble albuminose 2.216 Lignose 32.727 Fixed salts 17.976 Lost material .017 ------- 100.000

Previous to the studies of the above authors the seeds had been therapeutically tested by Delioux de Savignac and Professor Clouet. Heckel and Schlagdenhauffen have confirmed the febrifuge virtues of the seeds and are uncertain as to the active principle since they found no glucoside or alkaloid in their analysis. The antiperiodic properties are comparable with those of quinine and have even proved effective in some cases in which quinine failed. It seems quite clear that the tannin is the active principle which is the more probable because its anti-periodic virtues are now recognized by all therapeutists.

It is given in maceration or infusion, 2-15 grams of the seeds to 3 or 400 of water to be taken several times a day. The treatment causes no very marked physiological effects. It seems to act as a sedative to the nervous system.

Botanical Description.--An annual plant, .60-1 meter high. Root central with lateral rootlets. Stem straight, ramose. Leaves opposite, abruptly pinnate with a stylet in place of the odd leaflet. Leaflets, 5-6 pairs, the lower ones smaller, ovate, oblong, margins and lower face downy. Common petiole swollen at the base, 2 stipules and 1 glandule. Calyx, 5 unequal sepals. Corolla, 5 nearly equal petals, sulphur yellow, concave, the posterior one further developed. Two verticils of 5 stamens each. Of the 5 stamens superior to the sepals, 2 are fertile, larger and arched; of the other 5 stamens 4 are fertile and small. Pod compressed, linear, smooth, 5' long, containing many compressed, heart-shaped seeds, separated by thin partitions.

Habitat.--Common in Luzon. Blooms in October.

_Cassia alata_, L.

Nom. Vulg.--_Acapulco_, Sp.-Fil.; _Katandá_, _Gamut sa Buni_, _Sonting_, Tag.; _Sunting, Kansitás_, Vis.; _Pakayomkom-kastila_, Pam.

Uses.--This is one of the most popular Philippine remedies and its usefulness is vouched for by many physicians practicing in many different lands. Its antiherpetic properties are notable and the Tagalo name of the plant, "Gamut sa Buni," means literally "medicine for herpes." The natives use the juice of the leaf applied locally to the affected part. These properties have long been familiar to the Malays and to the Hindoos who in their medical works give the plant the Sanscrit name of "Dadrughna," meaning "to cure herpes." The Pharmacopoeia of Bengal recommends cassia in the form of an ointment made by mixing the crushed tender leaves with simple ointment. This preparation is, in our opinion, undesirable on account of its liability to become rancid and vaseline should be the excipient used. Another application for herpetic eruptions is the juice of the leaves mixed with an equal quantity of lemon juice. The Malays use the leaves dried in the sun, adding to them a little water and rubbing them briskly on the affected parts, the vigorous treatment being an important part of the cure.

The decoction of the leaves is a laxative and according to Mr. J. Wood the tincture has an action similar to that of senna. Dr. Pulney Andy of India states that the extract prepared from the tender leaves is a good substitute for extract of colocynth.

Mr. A. Porte claims to have obtained the best results with an acetic extract of the fresh leaves. The following is his formula:

Fresh leaves of _C. alata_ 100 grams. Acetic acid diluted in 2/3 water 450 grams.

Macerate 10 or 12 days, filter and express, then filter again and evaporate to the consistency of an extract.

The seeds contain vermifuge principles.

The activity of this plant in herpes is due to the chrysophanic acid contained in it. The more recent the eruption the more certain is the effect.

The following species, all of which grow in the Philippines, contain principles analogous to those of the _C. alata_, viz.: _C. sophera_, L. and _C. tora_, L., called in Tagalo _manimanihan_.

Botanical Description.--A shrub, 7-9° high, with a straight, ramose trunk 3-4' in diameter. Leaves 1 1/2-2° long, opposite, abruptly pinnate, a thick stylet taking the place of the odd leaflet. Leaflets 10-13 pairs, the smaller ones 1-2' long. Common petiole with 2 horizontal stipules at the base. Flowers in conspicuous, erect racemes. Calyx, 5 free concave, unequal sepals. Corolla, 5 petals of a beautiful yellow color. Stamens perigynous, 10 in number, 3 upper ones very small and frequently sterile, 3 lower very large. The bilocular anthers open by 2 pores. Ovary many-ovuled with filiform style. Pod long with 2 prominent wings on the sides and many seeds which slightly resemble a cross with blunt ends.

The _C. sophera_, L., is characterized by 10 stamens, all fertile and a smooth, linear, bivalved pod full of seeds separated by false

## partitions. The _C. tora_, L., bears a quadrangular pod about 15

centimeters long by 2 in diameter.

Habitat.--Grows in all parts of the islands and is universally known by the natives. Blooms in May.

_Tamarindus Indica_, L.

Nom. Vulg.--_Tamarindo_, Sp.; _Sampalok_, Tag., Pam., Bik.; _Sambak_, _Sumalagi_, _Kamalagi_, Vis.; _Tamarind_, Eng.

Uses.--The pulp of the fruit is used to make a sort of sweet preserve and is very popular among the Filipinos. They prepare a refreshing drink from the pulp mixed with sweetened water and believing it to be beneficial to the liver, stomach and blood, they use too much of it. Its excessive use is rather prejudicial to the health, but given in moderation it is very efficient in allaying the thirst of fever patients. The pulp contains weak laxative properties and it is customary to administer it in solution with cream of tartar. Its chemical composition is as follows:

Citric acid 9.40 Tartaric acid 1.55 Malic acid 0.45 Potassium bitartrate 3.25 Sugar 12.50 Gum 4.70 Vegetable gelatin 6.25 Parenchyma 34.35 Water 27.55

(Vauquelin.)

At the end of any sickness, especially after labor, the first bath given to the convalescent is with a decoction of the leaves of the "sampaloc," to prevent convulsions, the native herb-doctors say.

Botanical Description.--A large tree, somewhat resembling the elm in contour, with leaves opposite, abruptly pinnate. Leaflets 12 or more pairs, linear, with a notch at the apex, entire, glabrous. Flowers yellow-white, spattered dark red, racemose. Calyx, 4 sepals. Corolla, 5 lanceolate petals with crispate borders. Stamens monadelphous, dividing into 7 filaments above. The ripe pod is chocolate color, oblong, slightly compressed, straight or curved, 6-15 centimeters long, full of a light-brown pulp in which rest the seeds enveloped in a cellular membrane. These seeds are flattened, almost quadrangular; testa hard, of a chestnut color, shiny and without albumen.

Habitat.--Very common everywhere in the islands. Blooms in May.

_Bauhinia malabarica_, Roxb. (_B. tomentosa_, Wall. and Blanco.)

Nom. Vulg.--_Alibangbang_, Tag., Vis., Pam.

Uses.--The leaves of this tree and of the species _B. tomentosa_, L., are quite acid and the Filipinos use them as an ingredient of many dishes. The fresh flowers possess anti-dysenteric virtues for which purpose they are given internally in infusion of 10-20 grams of the flowers to one-half liter of water. The decoction of the root bark is a common remedy for liver troubles along the coast of Malabar according to Rheede.

Botanical Description.--A tree 20° high, with leaves alternate, peltate, slightly cordate, orbicular, the apex divided into two large lobules with a stylet between them, glabrous above, somewhat downy beneath; 2 large, flat glandules are situated at the base. Petioles short. Flowers cymose. Peduncle long. Calyx inferior, funnelform, with 4-5 sepals as long as the corolla. Corolla, 5 petals. Stamens 10, 5 alternate ones longer than the others. Stigma thick, peltate, 2 lobules. Pod 1° long, with linear stalk, containing many seeds separated by filamentous isthmuses.

Habitat.--Common everywhere. Blooms in November.

LEGUMINOSÆ.

Mimosa Division.

_Entada scandens_, Benth. (_E. Pursoetha_, DC. and Blanco.)

Nom. Vulg.--_Gogo_, Tag.; _Bayogo_, _Balogo_, _Gohong bakay_, Vis. and Pam.; _Gilla Nuts_, Indo-Eng.

Uses.--The use made of the mashed bark of this tree is well known throughout the Philippines. Cut in strips and beaten thoroughly between stones it is sold under the name of "gogo"; it is macerated in water, to which it imparts a reddish color, and forms a substitute for soap. The Filipinos use this preparation for bathing, especially the hair, for which purpose there is no more useful or simple preparation. It cures pityriasis, and renders the hair very soft, without drying it too much as is usually the case with soap. The natives use it in treating the itch, washing the affected parts with the maceration and at the same time briskly rubbing them with the bark; in this way they remove the crusts that shield the acari. The treatment is successful in direct proportion to the energy of rubbing.